Long Dan Xie Gan Wan: Calm the Liver

Long Dan Xie Gan Wan – Clear Liver Heat, Calm the Mind, and Drain Dampness Naturally

Feeling Overheated, Irritable, or Bogged Down by Dampness?

Long Dan Xie Gan Wan is a time-tested Chinese herbal formula that targets one of the most common imbalances in modern life—excess Liver fire and damp-heat. Whether you're dealing with red, itchy skin, tension headaches, mood swings, or urinary discomfort, this powerful formula helps clear internal heat, calm emotional irritability, and restore balance from the inside out. Made with potent herbs like Gentian root, Scutellaria, and Bupleurum, it's a go-to remedy for stress-driven symptoms and stubborn heat conditions.

Long Dan Xie Gan Wan is a traditional Chinese herbal formula used to clear excess Liver heat, drain damp-heat, and calm emotional or physical symptoms caused by internal fire. It supports relief from irritability, red eyes, headaches, urinary discomfort, skin eruptions, and stress-related tension. This formula is ideal for individuals with symptoms like anger, facial flushing, or damp-heat conditions such as UTIs and skin inflammation.

Known as the "Liver Fire-Draining Pill," it helps bring balance back to the body when the Liver and Gallbladder systems are overheated or overstimulated.


What Are the Benefits of Long Dan Xie Gan Wan?

Benefit Description
Clears excess Liver heat Helps ease anger, tension, irritability, and red face or eyes
Drains damp-heat from the lower burner Supports urinary tract health and relieves swelling or burning sensations
Cools rising Liver Yang Helps with dizziness, migraines, ear ringing (tinnitus), and facial tension
Supports healthy skin Traditionally used for rashes, itching, and inflammation tied to internal heat
Promotes detoxification pathways Gently moves stagnation in the Liver-Gallbladder system, especially after poor diet or emotional buildup

DSHEA Notice: These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.


Traditional Chinese Medicine (TCM) Theory

In TCM, Long Dan Xie Gan Wan targets Liver fire, damp-heat, and ascending Yang, patterns often triggered by poor diet, excessive alcohol, long-term stress, suppressed anger, or hormonal shifts. It clears heat from both the upper body (head, eyes, ears) and lower body (urinary, reproductive tract, skin).

Pattern Treated: Liver and Gallbladder fire with damp-heat in the lower burner.


Key Herbs in Long Dan Xie Gan Wan

Herb Function in Formula
Long Dan Cao (Gentian Root) Main herb to clear Liver fire and damp-heat
Huang Qin (Scutellaria) Cools and detoxifies the upper body
Zhi Zi (Gardenia Fruit) Clears heat and damp from all three burners
Chai Hu (Bupleurum Root) Moves Liver Qi, prevents stagnation from buildup
Mu Tong (Akebia Stem) Drains dampness, promotes urination
Ze Xie (Alisma Rhizome) Clears heat from lower Jiao and supports fluid movement
Dang Gui (Angelica Sinensis) Nourishes blood to protect against over-dispersion from heat clearing
Sheng Di Huang (Rehmannia) Cools blood, nourishes Yin, balances dryness
Gan Cao (Licorice Root) Harmonizes the formula, eases spasms and inflammation

How to Use Long Dan Xie Gan Wan

✅ Standard Dosage

  • 6–8 teapills per dose

  • 2 to 3 times per day

  • Take with warm water, preferably between meals


Best Times to Take

  • Morning or early afternoon, especially if experiencing irritability or heat symptoms

  • For urinary or skin issues, take consistently at the same times daily

  • Not usually taken before bed due to its energizing and clearing nature


How Long to Take It Before I See Results 

  • Acute flare-ups: 3–7 days, or until symptoms ease

  • Chronic imbalances: 2–4 weeks under guidance

  • Maintenance: Rotate with cooling or harmonizing formulas to avoid over-cooling


Who Should Adjust the Dosage?

  • Sensitive individuals:
    Start with 4–5 pills per dose, especially if prone to digestive sensitivity

  • Children or elderly:
    Use a reduced dose under supervision

  • Women during menstruation:
    May continue, but reduce dose if chills, fatigue, or excess bleeding occurs

  • Taking warming tonics or blood builders:
    Space doses apart to avoid conflicting actions


❓ What Is Long Dan Xie Gan Wan Best Used For?

Long Dan Xie Gan Wan is traditionally used when heat is rising or trapped in the Liver or lower Jiao. It’s ideal for people who feel overheated, irritated, congested, or inflamed—physically or emotionally.


Liver Fire & Emotional Heat

  • Anger, short temper, explosive moods

  • Red eyes, facial tension, neck stiffness

  • Headaches and migraines with a pulsing sensation


Damp-Heat in the Lower Body

  • Urinary pain or burning

  • Dark or cloudy urine

  • Vaginal discharge or itching (TCM pattern-related)

  • Damp skin conditions or oozing rashes


Rising Liver Yang or Qi Stagnation

  • Tinnitus, dizziness, blurred vision

  • Stress that “boils over”

  • Hormonal or liver-related skin eruptions


Ideal For:

  • People under chronic stress who feel “internally hot”

  • Individuals prone to rashes, UTIs, or emotional outbursts

  • Those with symptoms tied to Liver Qi stagnation turning into heat


⚠️ When to Avoid or Pause Use

  • During cold or deficiency conditions (fatigue, pale tongue, weak digestion)

  • If you experience loose stools or chills, stop and consult a practitioner

  • Not intended for long-term use unless monitored by a licensed herbalist


Shop Long Dan Xie Gan Wan

✅ Traditional Gentian-Based Formula

✅ Trusted GMP-Certified Herbal Source

✅ Non-GMO, Gluten-Free, No Fillers or Dyes

Buy Long Dan Xie Gan Wan Now » See All Sizes Below 


Real Customer Reviews

“This helped my skin clear up and reduced my stress headaches within a few days.”
“I use this anytime I feel hot and irritable—amazing for hormonal heat.”
“This formula works great when I feel Liver Qi stagnation building up from frustration.”


Why Buy From 1st Chinese Herbs?

  • Bulk and teapill formulas backed by real practitioner experience

  • Transparent educational support and guidance

  • Satisfaction guarantee with decades of trusted service

  • Fast shipping + real customer service


Summary

Long Dan Xie Gan Wan is one of TCM’s most powerful and reliable formulas for clearing excess heat, draining dampness, and restoring clarity in both body and mind. It’s ideal for modern stress-driven imbalances that show up as inflammation, irritability, and internal fire.


PubMed & Clinical Research on Long Dan Xie Gan Wan

1. Systematic Review & Meta‑Analysis: Insomnia Treatment

  • Analyzed 13 RCTs (1,181 participants) comparing Long Dan Xie Gan Tang (LDXGT) to conventional Western insomnia treatments

  • Found significantly higher effectiveness rates (Odds Ratio 4.32, 95% CI 3.05–6.13, P < .00001) and higher cure rates (OR 2.67, 95% CI 2.04–3.48, P < .00001) PubMed+11PubMed+11PubMed+11

  • Reported few adverse effects and no serious safety issues


2. Meta‑Analysis: Herpes Zoster Adjuvant Therapy

  • Reviewed 9 RCTs (821 patients) using LDXGB as adjunct to standard herpes zoster therapy

  • Showed faster blister resolution (WMD –1.31 days), crust formation (WMD –1.91), and pain resolution (WMD –2.13), plus reduced post‑herpetic pain risk (RR 0.28) compared to standard care alone PubMed+1PubMed+1

  • Evidence certainty ranged from low to moderate


3. Experimental Study: Viral Inactivation

  • In vitro results demonstrated that Long Dan Xie Gan Tan extract inhibits HSV‑1 and HSV‑2 viruses by inactivating infectivity in dose- and time-dependent manner

  • No cytotoxic effect on Vero cells at ≤ 2,000 µg/mL (IC₅₀ values: ~257.5 µg/mL for HSV‑1; ~494.6 µg/mL for HSV‑2) PubMedScienceDirect+12PubMed+12PMC+12


4. Animal Study: Liver Injury & Insulin Resistance

  • Longdan Xie Gan Tang in rat model reduced olanzapine-induced liver damage and insulin resistance, regulating inflammatory pathways via the ACE2/Ang(1–7)/Mas axis

  • Improved markers including ALT/AST, HOMA-IR, and inhibited NF-κB pathway activation PubMed+3PubMed+3ScienceDirect+3


5. Dermatological Application: Eczema

  • In a clinical trial with eczema patients, LDXGT showed greater improvement compared to standard Western medicine in reducing rash severity and itchiness

  • Suggests strong anti-inflammatory and heat-clearing benefits in skin conditions associated with damp-heat PubMed+3PMC+3PubMed+3ResearchGate+3Treasure of the East+3PubMed+3

 

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