Lyme Disease Frequently Asked Questions

Lyme Disease, Bacterial Infections, Tick Bites
Lyme disease is a bacterial infection transmitted to humans through the bite of infected black-legged ticks. These ticks are commonly found in grassy and wooded areas. When it comes to prevention, it is crucial to take measures to avoid tick bites. This includes wearing protective clothing, using insect repellent, and conducting regular tick checks after spending time outdoors. If one does contract Lyme disease, there are various herbs that may help alleviate symptoms. These include garlic, Japanese knotweed, and cat’s claw, which have shown potential in combating the infection. Symptoms of Lyme disease may vary, but commonly include fatigue, fever, headache, muscle and joint aches, and swollen lymph nodes. One distinctive hallmark of Lyme disease is the appearance of a bullseye rash known as erythema migrans. This rash expands slowly and may have a central clearing. If anyone experiences these symptoms after getting a tick bite or spending time in tick-infested areas, it is important to seek medical attention promptly.
ticks, lyme disease What is Lyme disease? 
Lyme disease is a tick-borne disease caused by the bites of infected ticks. The bacterium Borrelia burgorferi in the United States and Borrelia afzelii in Europe. In the United States, deer ticks (Ixodes scapularis) and western blacklegged ticks (Ixodes pacificus) spread the disease. Lyme disease has a variety of symptoms, including a red rash, fatigue, chills, headachesarthritic pains in joints, and swollen lymph nodes.
symptoms of tick bitesWhat are the symptoms of Lyme disease?
Lyme disease has an array of symptoms and is often hard to diagnose. Here are some of the more common symptoms of Lyme:

Bull’s Eye Rash: A telling symptom of Lyme disease is a “bull’s eye” rash that gradually grows larger over a period of several days. This rash is known as Erythema migrans (EM). This rash occurs in the vast majority of persons infected with Lyme disease, around 70% of patients. Although the average time it takes for this rash to show is around seven days, it can take as few as three or as many as twenty days to develop. The rash typically feels warm to the touch but not itchy or painful.

Arthritic Pain: Lyme disease often causes patients pain and/or stiffness (arthritis) in their larger joints like knees, elbows, ankles, and wrists. Arthritis occurs in about 31% of patients according to the CDC.

Facial (Bell’s) Palsy: Sometimes patients exhibit a loss of muscle tone on one or both sides of the face. Bell’s palsy occurs in approximately 9% of patients.

Heart Problems: In some rare cases, Lyme bacterium can travel to the heart and cause Lyme carditis. This affects the way that the electrical signals travel between the upper and lower chambers—a process that may interfere with a patient’s heart beat and thus lead to something called “heart block.”

Cognitive Defects: Many Lyme patients complain about a loss of mental function or capacity.

Meningitis: Meningitis is an inflammation of the meninges (or membranes) that surround your brain and spinal cord. Meningitis or encephalitis occurs in approximately 1-2% of patients.

Fatigue: Many Lyme patients experience extreme fatigue or a loss in usual energy.

How do you get Lyme disease?
Lyme disease is transmitted to humans through the bite of infected black-legged ticks (Ixodes scapularis in the Eastern U.S. and Ixodes pacificus in the Western U.S.), which carry the bacterium Borrelia burgdorferi. Here's how you can contract it:

Tick Bite: Ticks become infected when they feed on animals that carry the Lyme disease bacteria, such as mice, birds, or deer. When an infected tick attaches to a human and remains attached for 36 to 48 hours or more, it can transmit the bacteria.

Areas of High Risk: Ticks are commonly found in grassy, bushy, or wooded areas, especially in regions where Lyme disease is prevalent. Spending time in these environments increases the risk of encountering an infected tick.

Tick Attachment: Ticks often attach to hidden areas like the scalp, armpits, or groin.
They must be attached for a prolonged period, usually 24 to 48 hours, to effectively transmit the bacteria.

Seasonal Activity:
Ticks are most active during the spring and summer months, which is when most Lyme disease cases occur. To reduce the risk of Lyme disease, it's important to take preventive measures such as using tick repellents, wearing protective clothing, and conducting thorough tick checks after spending time in areas where ticks are likely to be present.


How is Lyme disease diagnosed?

Clinical EvaluationSymptom Assessment: Doctors will review your symptoms, including any characteristic signs like the erythema migrans rash (a red, expanding bullseye-shaped rash).

Medical History: A history of possible exposure to ticks, particularly in areas known for Lyme disease, is considered.

Laboratory TestingInitial Screening (ELISA Test):
The Enzyme-Linked Immunosorbent Assay (ELISA) test is often the first step to detect antibodies against Borrelia burgdorferi, the bacterium that causes Lyme disease.

Confirmatory Testing (Western Blot Test):
If the ELISA test is positive or equivocal, a Western Blot test is usually performed to confirm the diagnosis by detecting specific antibodies.

PCR Testing:
In some cases, Polymerase Chain Reaction (PCR) tests may be used to detect bacterial DNA in body fluids, such as blood or joint fluid.

Early Diagnosis and Treatment:
When Lyme disease is diagnosed early, usually within a few weeks of a tick bite, it can often be cured with a course of antibiotics. 
Common antibiotics used include doxycycline, amoxicillin, or cefuroxime, typically taken for 10 to 21 days. Early treatment is highly effective in eliminating the infection and preventing complications.

Late-Stage Lyme Disease: If Lyme disease is not treated promptly, it can progress to a late stage, where it may cause more severe symptoms, including arthritis, neurological issues, and heart problems.
Even in late stages, antibiotics can be effective, although longer treatment courses may be required.
Some individuals may experience persistent symptoms despite treatment, a condition known as Post-Treatment Lyme Disease Syndrome (PTLDS).

Post-Treatment Considerations: PTLDS involves lingering symptoms such as fatigue, joint pain, and cognitive difficulties. The exact cause of PTLDS is not well understood, and it is not typically due to ongoing infection. Symptoms usually improve gradually over time, and supportive care, including physical therapy and pain management, may be beneficial.

Importance of Preventive Measures: Preventing tick bites and promptly removing attached ticks reduces the risk of developing Lyme disease. Early recognition of symptoms and seeking medical attention quickly are key to effective treatment and cure.

Potential for Recurrence:
Reinfection can occur if you are bitten by another infected tick. It is important to take preventive measures, especially in areas where Lyme disease is common.
In summary, while most cases of Lyme disease can be effectively treated and cured, timely intervention is crucial. If you suspect you have Lyme disease or have been bitten by a tick, it’s important to seek medical advice promptly to ensure the best possible outcome.
 
What is the herbal treatment for Lyme disease?

Herbal Treatment for Lyme Disease 
Cat's Claw (Uncaria tomentosa):
    Properties: Anti-inflammatory, immune-modulating.
    Uses: Helps reduce inflammation and supports the immune system in fighting the infection.

Dan Shen (Salvia Miltiorrhiza Radix):

 Properties: Cardiovascular, liver function
    Uses: Helps reduce inflammation and neuroprotective benefits

Huang Qin Scutellaria Baicalensis Root):
    Properties: Anti-inflammatory, Antimicrobial Properties 
    Uses: Helps reduce inflammation and supports the immune system in fighting the infection.

Japanese Knotweed (Polygonum cuspidatum):
   Properties: Rich in resveratrol, anti-inflammatory, antimicrobial.
   Uses: Supports immune function and combats Lyme bacteria.

Andrographis (Andrographis paniculata):
    Properties: Antibacterial, immune-boosting.
    Uses: Used for its broad-spectrum antimicrobial properties and to enhance immune response.

Sarsaparilla (Smilax spp.):
    Properties: Detoxifying, anti-inflammatory.
    Uses: Aids in detoxification and reduces Herxheimer reactions (a reaction to endotoxins released by the death of harmful bacteria).

Garlic (Allium sativum):
    Properties: Antimicrobial, immune-supportive.
    Uses: Known for its strong antibacterial and antifungal properties.

Astragalus (Astragalus membranaceus):
    Properties: Immune-boosting, anti-inflammatory.
    Uses: Strengthens the immune system and helps prevent infections.

Turmeric (Curcuma longa):
  Properties: Anti-inflammatory, antioxidant.
  Uses: Reduces inflammation and oxidative stress in the body.

Ginger (Zingiber officinale):
    Properties: Anti-inflammatory, digestive aid.
   Uses: Reduces inflammation and supports digestive health, which can be compromised in Lyme disease.

Milk Thistle (Silybum marianum):
    Properties: Detoxifying, liver-supportive.
    Uses: Helps in liver detoxification and supports liver function.

Ashwagandha (Withania somnifera):
   Properties: Adaptogen, immune-supportive.
   Uses: Helps in managing stress and supports immune function.

Cordyceps Mushroom:
    Properties: Immune-modulating, energy-enhancing.
   Uses: Supports immune function and boosts energy levels.

Reishi Mushroom (Ganoderma lucidum):
  Properties: Immune-supportive, anti-inflammatory.
  Uses: Strengthens the immune system and reduces inflammation.

Licorice Root (Glycyrrhiza glabra):
    Properties: Anti-inflammatory, immune-modulating.
    Uses: Supports adrenal function and reduces inflammation.

Han Fang Ji (Stephania Tetrandrae Root):
  Properties: Anti-inflammatory, Diuretic Properties
    Uses: Reduces inflammation.


What are the long-term effects of Lyme disease?
Lyme disease, if not diagnosed and treated early, can lead to a range of long-term complications and persistent symptoms. These effects vary in severity and can impact multiple systems in the body. Here’s a detailed overview of the potential long-term effects: 

Chronic Lyme Disease Symptoms:
Persistent symptoms such as fatigue, joint pain, and cognitive difficulties can continue for months or even years after initial treatment.   These symptoms are often referred to as Post-Treatment Lyme Disease Syndrome (PTLDS).

Arthritis:
Lyme disease can cause Lyme arthritis, which typically affects the knees and other large joints.
Symptoms include severe joint pain, swelling, and sometimes lasting joint damage if not treated promptly.

Neurological Issues:
Known as Lyme neuroborreliosis, this can include problems such as meningitis, facial palsy (Bell's palsy),    and peripheral neuropathy.
Long-term effects may include memory problems, mood changes, and sleep disturbances.

Cardiac Complications:
Lyme carditis can occur, leading to irregular heartbeats, inflammation of the heart (myocarditis), and, in severe cases, heart failure.  Symptoms may include palpitations, chest pain, and shortness of breath.

Cognitive Dysfunction:
Also known as “Lyme brain,” this can involve difficulties with memory, concentration, and problem-solving.
Some patients experience long-term brain fog, which can affect daily activities and quality of life.

Chronic Fatigue:
Many individuals report prolonged and severe fatigue that can interfere with normal activities and is not relieved by rest.   This can be a significant aspect of PTLDS, affecting overall vitality and productivity.

How can I prevent Lyme disease?

Preventing Lyme disease primarily involves avoiding tick bites, as ticks are the main carriers of the Borrelia burgdorferi bacterium that causes the disease. Here are several effective strategies to help reduce your risk: 
1. Avoid Tick-Infested Areas 
Stay on Trails: When hiking or walking in wooded or grassy areas, stay in the center of the trails and avoid brushing against vegetation.

Avoid Tall Grass: Ticks are often found in tall grass and bushy areas, so minimize time spent in these environments. 

2. Use Tick Repellents 
Apply to Skin: Use insect repellents that contain DEET (20-30%) on exposed skin. Follow the manufacturer’s instructions for safe application.

Apply to Clothing: Treat clothing and gear with products containing permethrin, which repels and kills ticks. 

3. Wear Protective Clothing 
Long Sleeves and Pants: Wear long-sleeved shirts and long pants to reduce skin exposure to ticks.

Light-Colored Clothing: Wear light-colored clothing to make it easier to spot ticks.

Tuck in Clothes: Tuck pants into socks or boots and shirts into pants to create barriers that prevent ticks from reaching your skin. 

4. Perform Tick Checks 
Check Yourself: After spending time outdoors, thoroughly check your body for ticks. Pay special attention to hidden areas like the scalp, behind the ears, armpits, groin, and behind the knees.

Check Your Pets: Regularly check pets for ticks, as they can carry ticks into your home. 

What is a Lyme disease rash (erythema migrans)?
Description:
Erythema migrans is a red, expanding rash that typically appears at the site of the tick bite.

  • The rash often starts as a small red bump and expands over several days to weeks, forming a circular or oval shape.

Appearance:

  • It is commonly described as looking like a "bullseye" or "target" due to its characteristic pattern: a red outer ring with a clearer center.
  • The rash can range in size but is typically larger than 5 cm (2 inches) in diameter. In some cases, it can become very large, covering a significant area of the body.

 Can Lyme disease affect the nervous system?

Yes, Lyme disease can affect the nervous system. This condition, known as Lyme neuroborreliosis, occurs when the Borrelia burgdorferi bacteria spread to the central and peripheral nervous systems. Here’s a detailed explanation of how Lyme disease can impact the nervous system and the potential symptoms: 
Impact on the Nervous System 
Neurological Involvement:
Central Nervous System (CNS): Lyme disease can cause inflammation of the brain and spinal cord, leading to various neurological symptoms.

Peripheral Nervous System (PNS): The infection can also affect nerves outside the brain and spinal cord, leading to issues with sensation and movement.

Common Neurological Symptoms:
Meningitis: Inflammation of the membranes surrounding the brain and spinal cord can cause severe headaches, stiff neck, fever, and sensitivity to light.

Facial Palsy (Bell's Palsy): One of the most distinctive signs is the sudden weakness or paralysis of the facial muscles, typically on one side of the face, causing drooping and difficulty with facial expressions.

Radiculoneuritis: This involves inflammation of the nerve roots, leading to pain, numbness, or tingling sensations that may affect the back, arms, or legs.

Long-term Neurological Effects:
Cognitive Impairment: Memory problems, difficulty concentrating, and other cognitive issues can arise, sometimes referred to as “Lyme brain.”

Mood Disorders: Anxiety, depression, and mood swings can occur due to the infection’s impact on the brain.

Peripheral Neuropathy: Persistent symptoms like numbness, tingling, or burning sensations in the extremities may develop.


How long does it take to recover from Lyme disease? 

The recovery time from Lyme disease can vary significantly from person to person and depends on several factors, including the stage of the disease at diagnosis, the timeliness of treatment, and the individual's overall health. Here’s a detailed explanation: 
Factors Affecting Recovery Time 

1.   Stage of Disease at Diagnosis:
Early-Stage Lyme Disease: If Lyme disease is diagnosed and treated promptly in its early stages, typically within a few weeks of a tick bite, most people recover fully within a few weeks to a few months after completing a course of antibiotics.

Late-Stage Lyme Disease: Recovery from later stages of Lyme disease, where the infection has spread to other parts of the body, such as joints, the nervous system, or the heart, may take longer and can be more complicated. 

What is post-treatment Lyme disease syndrome (PTLDS)?
Post-Treatment Lyme Disease Syndrome (PTLDS) is a condition that occurs in some individuals who have been treated for Lyme disease with antibiotics but continue to experience symptoms that can persist for months or even years after treatment. PTLDS is sometimes referred to as chronic Lyme disease, although this term can be controversial. Here’s a detailed explanation of PTLDS:

Understanding PTLDS
Definition:
PTLDS describes a collection of symptoms that persist after the standard antibiotic treatment for Lyme disease has been completed.
The symptoms are not due to active infection but may be a result of the body's lingering response to the initial infection.

Common Symptoms:

Fatigue: Severe and ongoing tiredness that does not improve with rest.

Joint and Muscle Pain: Persistent pain and swelling, especially in large joints like the knees.

Cognitive Issues: Memory problems, difficulty concentrating, and “brain fog.”

Sleep Disturbances: Problems with sleeping, including insomnia.

Mood Changes: Depression, anxiety, and irritability.

Neurological Symptoms: Numbness, tingling, and other sensory disturbances.

What are the risks of untreated Lyme disease?
Untreated Lyme disease can lead to serious and potentially long-term health complications. The risks increase the longer the infection is left untreated, affecting multiple systems in the body. Here’s a detailed explanation of the potential risks and complications: 
1. Chronic Lyme Disease 
Persistent Symptoms: Untreated Lyme disease can lead to a chronic condition where symptoms persist for months or even years. This can include severe fatigue, joint pain, and neurological issues.

Quality of Life: Chronic symptoms can significantly impact daily life, leading to decreased productivity and overall well-being. 

2. Arthritis and Joint Damage 
Lyme Arthritis: One of the most common complications of untreated Lyme disease is Lyme arthritis, characterized by severe joint pain and swelling, particularly in the knees.

Joint Damage: Chronic inflammation can lead to lasting damage to joints, resulting in reduced mobility and long-term pain. 

3. Neurological Complications 
Neuroborreliosis: The bacteria can spread to the nervous system, causing Lyme neuroborreliosis, which can include meningitis, facial palsy (Bell's palsy), and peripheral neuropathy.

Cognitive Impairment: Untreated infection can lead to problems with memory, concentration, and mental clarity, sometimes referred to as “Lyme brain.”

Severe Cases: In rare instances, untreated Lyme disease can lead to severe neurological complications such as encephalitis (brain inflammation) and myelitis (spinal cord inflammation). 

4. Heart Problems 
Lyme Carditis: The infection can affect the heart, leading to Lyme carditis. This can cause irregular heartbeats (arrhythmias), myocarditis (inflammation of the heart muscle), and even heart block, which can be life-threatening.


Understanding Lyme Disease Without a Rash 
Prevalence of the Rash:
The erythema migrans rash occurs in approximately 70-80% of people who are infected with Lyme disease.    This means that around 20-30% of individuals with Lyme disease do not develop a rash or do not notice it.

Symptoms Without a Rash:
Flu-Like Symptoms: Many people with Lyme disease may experience flu-like symptoms such as fever, chills, fatigue, muscle and joint aches, and headache.

Joint Pain: Pain and swelling in joints, particularly the knees, can occur even in the absence of a rash.

Neurological Symptoms: Some individuals may develop neurological issues such as facial palsy (Bell's palsy), meningitis, or peripheral neuropathy without ever having a rash.

Heart Problems: Lyme disease can also lead to Lyme carditis, which may cause irregular heartbeats, chest pain, and other cardiac issues without a rash.

How common is Lyme disease?
Lyme disease is the most common tick-borne illness in the United States and Europe, and its prevalence is increasing in many areas. The incidence of Lyme disease varies significantly by region, with higher rates in areas where ticks that carry Borrelia burgdorferi, the bacteria that cause the disease. 

Is Lyme disease contagious?
Children and adults who spend a lot of time outdoors, particularly in or near wooded areas in the northeast part of the country, are more likely to contract Lyme. There is concern that Lyme disease may be passed to the fetus by infected mothers. Pets can become infected with the disease as well and may carry infected ticks into areas where humans live. There are tick control products and other protective measures that can be used with pets although these may involve products containing harmful chemicals.
magnitude of ticks all over the world 
Where is Lyme disease most common?
In 2013, 95% of confirmed Lyme disease cases were reported from these states: Connecticut, Delaware, Maine, Maryland, Massachusetts, Minnesota, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island, Vermont, Virginia, and Wisconsin.
UPDATE:  
Lyme disease is most common in the Northern Hemisphere, especially in North America and Europe. In the United States, it is prevalent in the northeastern and upper Midwestern states, such as Connecticut, New York, Washington, Oregon, California, Kansas, Tennessee, Wisconsin, and Minnesota. However, cases have been reported in other regions as well. Lyme Disease is found all over the world. 
As for the spread of Lyme disease since 2015, it is difficult to provide precise global numbers. However, the Centers for Disease Control and Prevention (CDC) in the United States has reported an increase in the number of cases annually. In 2015, there were around 28,500 cases reported, and by 2019, the number increased to approximately 48,000 cases. It's important to note that these statistics represent only reported cases and the actual number of infections may be higher due to underreporting. 

I’ve heard that once you have Lyme disease, you always have it. Is this true?
No. Many patients who caught the infection in the early stages and completed their antibiotics recover quickly. Some patients that are treated in later stages may have some long-term effects including fatigue, arthritis, and difficulty thinking even after completing their antibiotic treatment. These symptoms generally improve on their own over time.

How many people get Lyme disease per year?
According to sources, anywhere from 30,000 to 300,000 people in the United States are infected with Lyme disease every year. Estimates vary greatly because many times the symptoms of Lyme disease align with other ailments (like arthritis or meningitis) and the Lyme goes undiagnosed. "Officials from the federal Centers for Disease Control and Prevention said Monday that about 300,000 people in the United States are diagnosed with Lyme disease each year—about 10 times as many as are officially reported."
 
For more information visit FAQ at the Center for Disease Control.
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https://www.healthvermont.gov/disease-control/tick-bite-illnesses/lyme-disease

https://www.vet.cornell.edu/animal-health-diagnostic-center/laboratories/serology-immunology/lyme-disease

https://www.niaid.nih.gov/diseases-conditions/lyme-disease